What is Sildenafil?
Sildenafil is highly effective for erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and other conditions related to blood flow. It is also known as a phosphodiesterase type 5 (PDE5) inhibitor.
How does Sildenafil work?
Sildenafil increases blood flow to the penis to help a man easily achieve and maintain an erection. This efficacy is due to inhibiting the action of the PDE5 enzyme, which breaks down cyclic guanosine monophosphate (cGMP), a molecule that relaxes the smooth muscle in the penis and increases blood flow.
Let’s understand the detailed working mechanism.
When a man is sexually stimulated, the release of nitric oxide (NO) causes an increase in cGMP levels in the penis. This leads to the relaxation of smooth muscle in the corpus cavernosum. By inhibiting the action of PDE5, Sildenafil helps to maintain high levels of cGMP, which promotes the relaxation of smooth muscle and increases blood flow to the penis.
You can buy Sildenafil in different dosages. However, the ideal dose for you can be evaluated by your doctor depending on your medical condition and other factors.
The standard dose for ED is 50 mg. You need to take it about 1 hour before sexual activity. But this can be adjusted up or down depending on your individual needs.
Sildenafil is available in the following dosages.
25 mg: This low dose is often prescribed for men on secondary medications that may interact with Sildenafil. It is also ideal for older men, patients with mild ED, or men with other medical conditions that may increase their risk of side effects. It can also be prescribed for men who are older or have mild ED.
50 mg: This is the standard dose for most men with ED. You have to take it 1 hour before sexual activity and can adjust the dose based on efficacy and any side effects.
100 mg: This is the highest dose of Sildenafil available. If your case does not respond well to lower doses, doctors may prescribe you 100mg. But, it is also associated with a higher risk of side effects. Thus, before you buy Sildenafil 100mg in UK, consult your doctor first.
How to Take Sildenafil Tablets?
Sildenafil tablets are usually taken by mouth about 1 hour before sexual activity. Here are the general guidelines for taking Sildenafil tablets:
- Take Sildenafil exactly as prescribed by your doctor. Never take more or less than the prescribed amount.
- Swallow the entite Sildenafil tablet without crushing, chewing, or breaking it.
- Take it with or without food, but not with a high-fat meal.
- Do not take Sildenafil more than once a day.
- Do not take Sildenafil more than once a day.
- It’s important to remember that Sildenafil will only work if you are sexually aroused. It won’t make you more sexually motivated.
- If you experience side effects such as chest pain, dizziness, or vision changes, stop taking the medication and contact your doctor right away.
How does it take Sildenafil to work?
Sildenafil typically starts to work within 30 to 60 minutes after it is taken, although the onset of action can vary depending on a number of factors, such as the individual’s metabolism, whether it is taken with food and the dosage.
Once taken, Sildenafil is absorbed into the bloodstream and begins to inhibit the action of the PDE5 enzyme, which increases the levels of cyclic guanosine monophosphate (cGMP) in the penis. This leads to the relaxation of smooth muscle in the corpus cavernosum, which promotes blood flow to the penis and helps to achieve and maintain an erection.
It’s important to note that Sildenafil will only work if the person taking it is sexually aroused. It does not increase sexual desire, and sexual stimulation is necessary for the medication to be effective.
The effects of Sildenafil can last for up to 4 to 5 hours after it is taken, although this can also vary depending on the individual. It’s important to follow your doctor’s instructions and not take more than the recommended dose, as this can increase the risk of side effects. Also, before you decide to buy Sildenafil in UK, consult your doctor for sure.
What are the side effects of Sildenafil?
Sildenafil, like all medications, can cause side effects in some people. Some of the most typical side effects of sildenafil are listed below:
- Nasal congestion
- Upset stomach
- Back pain
- Muscle aches
- Vision changes, such as a blue tinge the vision or blurred vision
- Rarely, sudden hearing loss or ringing in the ears (tinnitus)
These side effects wear off automatically within a few hours. However, if they persist for a long time, contact your doctor immediately.
In rare cases, Sildenafil can cause more serious side effects such as:
- An allergic reaction.
- Chest pain or an irregular heartbeat
- Prolonged and painful erection (priapism)
- sudden blindness in one or both eyes
In the event of such side effects, seek medical attention immediately.
Also, let your doctor know about your ongoing medications. It will help him decide if Sildenafil is the right medication for you or not.
FQA About Sildenafil UK
It is not ideal to consume such a high dose daily without a doctor’s advice. This maximum dose is typically only prescribed for men who do not respond to lower doses of the medication.
But if you do so without medical supervision, you may invite unwanted side effects. You may also experience irregular heartbeat or sudden hearing loss.
Sildenafil may not be suitable for everyone. It may interact under the following conditions:
Nitrates: Nitrates, including nitroglycerin or isosorbide dinitrate, can interact with the drug. If you are using nitrates for chest pain or heart problems, the combination can cause a dangerous drop in blood pressure.
Certain medications: Sildenafil can interact with alpha-blockers and some antibiotics to cause blood pressure drops.
Severe liver or kidney disease: People with severe liver or kidney disease may not be able to process Sildenafil properly.
Severe heart disease: Sildenafil can put extra strain on the heart. So, it may not be safe for people with severe heart disease.
History of stroke or heart attack: Sildenafil may not be suitable for patients with stroke or heart attack in the past.
Allergies: If you’re allergic to Sildenafil or any of its ingredients, do not take the medication.